Publications

Rotstein DL, Alroughani R, Arrambide G, Contentti EC, Chomba M, Fujihara K, Gilhus NE, Gouider R, Heckmann JM, Kim HJ, Li HF, Leite MI, Monif M, Siritho S, Thiel S, Vishnevetsky A, Viswanathan S, Vukusic S, Yamout B, Kümpfel T and Hellwig K. (2026) Current evidence and knowledge gaps in family planning and pregnancy in myasthenia gravis, NMOSD, and MOGAD. Lancet Neurology. https://doi.org/10.1016/S1474-4422(25)00479-X
Marrie RA, Maxwell CJ, Bolton JM, Söderling J, Bernstein CN, Krysko KM, McKay KA, Rotstein D, Deakin-Harb K and Razaz N. (2026) Incident and prevalent peripartum mental illness in mothers with multiple sclerosis and other chronic diseases in Sweden. Multiple Sclerosis and Related Disorders. https://doi.org/10.1016/j.msard.2026.107041
Momen AI, Freedman MS, Fadda G, Konig A, Lee L, Marrie RA, Morrow SA, McCombe JA, Parks NE, Smyth P, Casserly CS and Rotstein DL. (2026) Demographic and clinical characteristics of aquaporin-4 antibody positive neuromyelitis optica spectrum disorder in Canadian adults. Canadian Journal of Neurological Sciences. https://doi.org/10.1017/cjn.2026.10539
Marrie RA, Fakolade A, Maxwell CJ, Rotstein DL, Tremlett H, Yeh EA and Finlayson M. (2026) Setting priorities for how future research in multiple sclerosis in Canada considers equity, diversity and inclusion: A modified e-Delphi study. Multiple Sclerosis Journal – Experimental, Translational and Clinical. https://doi.org/10.1177/20552173251398975
Fijardo M, Xie JS, Rotstein D and Margolin E. (2025) Myelin oligodendrocyte glycoprotein-associated optic neuritis in a patient with systemic myasthenia gravis. Canadian Journal of Neurological Sciences. https://doi.org/10.1017/cjn.2025.10447
Li J, Vas N, Amezcua L and Rotstein DL. (2025) Multiple sclerosis in people of diverse racial and ethnic backgrounds: presentation, disease course, and interactions with disease-modifying therapy. CNS Drugs. https://doi.org/10.1007/s40263-025-01205-4
Chew E, Rotstein DL and Viswanathan S. (2025) Navigating a paradigm shift in the treatment of CNS demyelinating diseases in a middle-income country. Multiple Sclerosis and Related Disorders. https://doi.org/10.1016/j.msard.2025.106544
Marrie RA, Bolton JM, Ling V, Bernstein CN, Krysko KM, Li P, McKay KA, Razaz N, Rotstein DL, Deakin-Harb K and Maxwell C. (2025) Risk factors for incident peripartum mental illness in multiple sclerosis. Multiple Sclerosis. https://doi.org/10.1177/13524585251330109
Zabalza A, Thompson A, Rotstein DL, Bar-Or A and Montalban X. (2025) Multiple sclerosis and COVID-19: interactions and unresolved issues. Lancet Neurology. https://doi.org/10.1016/S1474-4422(25)00006-7
Gassan AA, Konig A, Nisenbaum R, Freedman MS, Lee L, Marrie RA, McCombe JA, Micieli J, Morrow SA, Parks NE, Smyth P and Rotstein DL. (2025) Comparison of vision-related quality of life in NMOSD and MOGAD. Multiple Sclerosis and Related Disorders. https://doi.org/10.1016/j.msard.2025.106392
Marrie RA, Bolton J, Ling YV, Bernstein C, Krysko KM, Li P, McKay KA, Pequeno P, Razaz N, Rotstein D, Deakin-Harb K and Maxwell CJ. (2025) Peripartum mental illness in mothers with multiple sclerosis and other chronic diseases in Ontario, Canada. Neurology. https://doi.org/10.1212/WNL.0000000000210170
Marrie RA, Fakolade A, Linton J, Maxwell CJ, Rotstein D, Schindell B, Tremlett H, Yeh A and Finlayson M. (2025) Characterizing the diversity of the multiple sclerosis population in Canada: a scoping review. Multiple Sclerosis Journal – Experimental, Translational and Clinical. https://doi.org/10.1177/20552173251321814
Munger KC and Rotstein DL. (2024) Racial and ethnic disease phenotype differences are driven by genetics: commentary. Multiple Sclerosis. https://doi.org/10.1177/13524585241301304
Carnero Contentti E, Rotstein D, Okuda DT and Paul F. (2025) How to avoid missing a diagnosis of neuromyelitis optica spectrum disorder. Multiple Sclerosis. https://doi.org/10.1177/13524585241292797
Chien C, Cruz E Silva V, Geiter E, Meier D, Zimmermann H, Bichuetti DB, Idagawa MI, Altintas A, Tanriverdi U, Siritho S, Pandit L, Dcunha A, Sá MJ, Figueiredo R, Qian P, Tongco C, Lotan I, Khasminsky V, Hellmann MA, Stiebel-Kalish H, Rotstein DL, Waxman L, Ontaneda D, Nakamura K, Abboud H, Subei MO, Mao-Draayer Y, Havla J, Asgari N, Skejø PB, Kister I, Ringelstein M, Broadley S, Arnett S, Marron B, Jolley AM, Wunderlich M, Green S, Cook LJ, Yeaman MR, Smith TJ, Brandt AU, Wuerfel J and Paul F. (2024) Aquaporin-4 immunoglobulin G-seropositive neuromyelitis optica spectrum disorder MRI characteristics: data analysis from the international real-world PAMRINO study cohort. Radiology. https://doi.org/10.1148/radiol.233099
Amezcua L, Rotstein D, Shirani A, Ciccarelli O, Ontaneda D, Magyari M, Rivera V, Kimbrough D, Dobson R, Taylor B, Williams M, Marrie RA, Banwell B, Hemmer B, Newsome SD, Cohen JA, Solomon AJ and Royal W. (2024) Differential diagnosis of suspected multiple sclerosis: considerations in people from minority ethnic and racial backgrounds in North America, northern Europe, and Australasia. Lancet Neurology. https://doi.org/10.1016/S1474-4422(24)00288-6
Lee S, Marrie RA, Fadda G, Freedman MS, Lee L, Muccilli A, Vyas MV, Konig A and Rotstein DL. (2024) Is there a prodrome to NMOSD? An investigation of neurologic symptoms preceding the first NMOSD attack. Multiple Sclerosis. https://doi.org/10.1177/13524585241275491
Rotstein DL, Freedman MS, Konig A, Lee L, Luo J, Maxwell C, Morrow SA, Tremlett H, Vyas MV and Marrie RA. (2024) Investigation of health care use and a possible prodrome before the first attack in NMOSD and MOGAD. Multiple Sclerosis. https://doi.org/10.1177/13524585241272939
Arnett S, Chew SH, Leitner U, Hor JY, Paul F, Yeaman MR, Levy M, Weinshenker BG, Banwell BL, Fujihara K, Abboud H, Dujmovic Basuroski I, Arrambide G, Neubrand VE, Quan C, Melamed E, Palace J, Sun J, Asgari N and Broadley SA. (2024) Sex ratio and age of onset in AQP4 antibody-associated NMOSD: a review and meta-analysis. Journal of Neurology. https://doi.org/10.1007/s00415-024-12452-8
Vyas MV, Kapral MK, Alonzo R, Fang J and Rotstein DL. (2024) Proportion of life spent in Canada and the incidence of multiple sclerosis in permanent immigrants. Neurology. https://doi.org/10.1212/WNL.0000000000209350
Chatanaka MK, Avery LM, Pasic MD, Sithravadivel S, Rotstein D, Demos C, Cohen R, Gorham T, Wang M, Stengelin M, Mathew A, Sigal G, Wohlstadter J, Prassas I and Diamandis EP. (2024) The relationship between serum astroglial and neuronal markers and AQP4 and MOG autoantibodies. Clinical Proteomics. https://doi.org/10.1186/s12014-024-09466-9
Budhram A, Rotstein DL, Yang L and Yeh EA. (2024) Myelin oligodendrocyte glycoprotein antibody titers by fixed cell-based assay: positive predictive value and impact of sample collection timing. Frontiers in Neurology. https://doi.org/10.3389/fneur.2024.1380541
Rotstein DL, Freedman MS, Lee L, Marrie RA, Morrow SA, McCombe JA, Parks NE, Smyth P, Konig A and Vyas MV. (2024) Predicting time to serologic diagnosis of AQP4+ NMOSD based on clinical factors and social determinants of health. Multiple Sclerosis and Related Disorders. https://doi.org/10.1016/j.msard.2024.105434
Hosseini-Moghaddam S, Marrie RA, Wolfson C, Carruthers R, Freedman MS, Morrow S, Lee L, Nisenbaum R, Konig A, Magalhaes S and Rotstein DL. (2023) A Canadian case control study investigating demographic and environmental factors associated with MOGAD. Multiple Sclerosis and Related Disorders. https://doi.org/10.1016/j.msard.2023.105023
Rotstein DL, Gyang TV and Ontaneda D. (2023) Making sure multiple sclerosis counts and is counted for all—an update on multiple sclerosis prevalence by race and ethnicity in the United States. JAMA Neurology. https://doi.org/10.1001/jamaneurol.2023.0469